Circadian oscillations, over approximately 24-h, are very important and among the most studied physiological oscillations. To evaluate the presence and significance of 24-h oscillations, physiological time distributed data are often set to a cosinor model using a wide range of irregularly updated (very often outdated) native apps which have problem with modern operating systems. Therefore, for users not familiar with MATLAB, R or other programming languages, we created Cosinor.Online application. The application is running in modern web browsers and is hosted on remote servers running 24/7.
Cosinor.Online, cosinor on the web:
- It is a simple web-based application, which can be used for a quick and simple inspection of 24-h (or whatever you choose) oscillations of various biological and physiological time distributed data.
- The application code is written in PHP and time distributed data are handled using a MySQL database.
- Loading data is easy, just copy and paste columns from an Excel file to the webform.
- Analysis results contain also a unique ID identifier, which allows users to reopen data and results repeatedly over one month or remove their data from the MySQL database, for free.
More about the application in the preprint on BioRxiv
, doi: https://doi.org/10.1101/805960
Molcan, L. (2019). Time distributed data analysis by Cosinor. Online application. bioRxiv